| Alumni Cross Country Run | Saturday, August 14, 2021 | Seneca Park | |
| Tailgate, Glaser Plaza Dedication & Football Reunions | Friday, September 3, 2021 | St. X Stadium (Gate 1) | |
| Alumni Hall of Honors | Wednesday, October 20, 2021 | Marriott Louisville East | |
| KHSAA 1995 State Football Champs Reunion | Saturday, December 4, 2021 | Kroger Field | |
| Alumni Phonathon | February 28-March 30, 2021 | St. X | |
| Alumni Retreat | March 26-27, 2022 | St. Meinrad Archabbey | |
| 50-Year Club Lunch | Thursday, June 9, 2022 | Crowne Plaza Hotel |